Anti-MKI67 Antibody

The Ki-67 protein (encoded by the MKI67 gene) is a nuclear marker of cell proliferation widely used in cancer research, tumor pathology, and cell biology. This unconjugated rabbit polyclonal reagent from Antibodies.com is validated for Western blot, immunohistochemistry, and immunofluorescence workflows in human samples, supplied as 100 µl in a single-use vial.

As a proliferation marker, Ki-67 is expressed throughout the active phases of the cell cycle (G1, S, G2, and M) and is absent in quiescent G0 cells, making it valuable for assessing growth fraction in tumor sections, evaluating mitotic activity in tissue microarrays, and characterizing proliferative responses in cultured cell lines. The polyclonal format provides recognition of multiple epitopes on the large Ki-67 protein, useful when robust signal is needed across varied sample preparations including formalin-fixed paraffin-embedded tissue, fresh-frozen sections, and adherent cultures.

Researchers studying oncology, stem cell biology, and tissue regeneration rely on Ki-67 staining to distinguish actively dividing populations from resting cells, supporting studies of prognosis, treatment response, and developmental biology. The unconjugated format from Antibodies.com allows flexibility in choosing secondary detection reagents, fluorophore conjugates, and enzyme labels matched to specific experimental designs in research use only settings.