Anti-MIP 1 alpha Antibody [116]

This Mouse monoclonal antibody (clone 116) from Antibodies.com recognizes human Macrophage Inflammatory Protein 1 alpha (MIP-1 alpha), a CC-family chemokine also referred to as CCL3. The target protein is secreted by macrophages and additional leukocyte populations during inflammatory responses, signalling through the CCR1 and CCR5 receptors to recruit monocytes, T lymphocytes, and NK cells to sites of infection or tissue damage. The unconjugated IgG2a reagent is provided as a 100 µg lyophilised preparation intended for research use in ELISA workflows aimed at detecting or quantifying this chemokine. Lyophilisation offers flexibility in reconstitution and storage, while the unconjugated format allows researchers to conjugate the antibody to a reporter enzyme, biotin, or fluorophore of their choosing. Because CCL3 is implicated in acute and chronic inflammation as well as in chemokine receptor signalling studies, this reagent supports investigations of cytokine release patterns, leukocyte trafficking, and host defence mechanisms in cell-based and biochemical research models.