Anti-MIER2 Antibody

MIER2 (Mesoderm Induction Early Response 1, Family Member 2) is a nuclear transcriptional regulator implicated in chromatin remodeling through its interactions with histone deacetylase complexes. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against MIER2 and validated for detection of the human target in western blot and immunohistochemistry workflows.

The reagent is supplied as a 100 µl liquid aliquot in a vial and is intended for laboratories investigating MIER2 expression in cell and tissue samples. MIER2 has been studied in the context of breast cancer biology, where altered expression patterns have been linked to tumor progression, as well as in developmental biology research related to mesoderm specification. Researchers characterizing HDAC-associated transcriptional repression pathways also use anti-MIER2 reagents to probe chromatin-modifying complexes.

For western blot applications, the antibody recognizes endogenous MIER2 in whole-cell lysates, while immunohistochemistry enables localization studies in formalin-fixed, paraffin-embedded tissue sections. The polyclonal format offers recognition of multiple epitopes on the MIER2 target, which can be advantageous when probing protein variants. Store at -20°C and aliquot upon receipt to minimize freeze-thaw cycles and preserve reagent integrity for long-term experimental use.