Anti-MFSD2A Antibody

Polyclonal antibodies targeting MFSD2A from Antibodies.com are raised in rabbit hosts and supplied unconjugated in 100 µl vials for Western blot and immunohistochemistry workflows on human samples. MFSD2A is a twelve-pass transmembrane lysophosphatidylcholine symporter that shuttles omega-3 fatty acid precursors across the blood-brain barrier endothelium, where its abundance is widely used as a marker of barrier integrity in neurovascular research.

Independent groups have linked MFSD2A loss-of-function to lethal microcephaly syndromes and have explored its role in glioblastoma, hepatic lipid handling, and adipocyte metabolism, making this reagent relevant to studies of brain lipid uptake, BBB dysfunction in neurodegenerative disease, and tumor vascular biology. The polyclonal format provides multi-epitope coverage for detecting endogenous MFSD2A in tissue sections and lysates, and the unconjugated format allows pairing with HRP- or fluorophore-conjugated secondary reagents chosen by the end user.

Because each application has its own matrix effects, working dilutions should be determined empirically against positive control tissue or cell lysates known to express MFSD2A. Standard polyclonal antibody handling applies, including brief centrifugation before use and aliquoting on first thaw to limit repeated freeze-thaw cycles during long-term storage.