Anti-MFN2 Antibody

Manufactured by Antibodies.com, this rabbit polyclonal antibody targets Mitofusin-2 (MFN2) and is supplied at 50 µl per vial at a concentration of 1.0 mg/mL in a phosphate-buffered saline formulation (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, without Mg²⁺ and Ca²⁺. The immunogen is a recombinant human MFN2 protein, and the reagent is affinity-purified against the immunogen to ensure selective recognition of endogenous total MFN2 protein. Conceived for use in Western blot (WB) and immunohistochemistry (IHC), the unconjugated antibody has been validated for cross-reactivity with Human, Mouse, and Rat samples, making it suitable for comparative studies of mitochondrial outer-membrane dynamics across species. The host species is Rabbit, and the clonality is polyclonal, providing a broad epitope coverage that is useful when working with denatured or partially degraded samples. For optimal stability, the antibody should be stored at −20 °C, where the glycerol-containing buffer protects against freeze–thaw damage. Each preparation is intended strictly for research use and is not validated for diagnostic or therapeutic applications. Researchers studying mitochondrial fusion, Charcot–Marie–Tooth disease type 2A, mitophagy, or metabolic regulation will find this reagent a reliable tool for detecting total endogenous MFN2 levels in lysates and tissue sections, while the unconjugated format offers flexibility to conjugate the antibody with fluorophores, biotin, or enzymes according to the user's downstream assay requirements.