Anti-MFN2 Antibody

The Anti-MFN2 Antibody from Antibodies.com is a rabbit polyclonal reagent raised against Mitofusin 2, a dynamin-like GTPase embedded in the outer mitochondrial membrane that drives mitochondrial tethering and fusion in mammalian cells. This unconjugated primary antibody is validated for Western blot and immunohistochemistry workflows and cross-reacts with human, mouse, and rat samples, enabling comparative studies across cell-line panels and rodent tissue models. The product is supplied as 100 µl of working solution, suitable for immunoblotting of mitochondrial-enriched lysates and for IHC labeling of neural, cardiac, and skeletal muscle tissues where MFN2 expression is biologically relevant. Researchers interrogating mitochondrial dynamics, mitophagy, and Charcot-Marie-Tooth disease type 2A commonly deploy this reagent to evaluate fusion-fission balance, endoplasmic reticulum-mitochondria contact sites, and remodeling of the mitochondrial network under metabolic or oxidative challenge. The polyclonal format allows recognition of multiple epitopes on the MFN2 protein, supporting reliable detection in denaturing gels and in lightly fixed preparations.