Anti-MFE-2 Antibody

This rabbit polyclonal primary antibody from Antibodies.com is raised against human multifunctional enzyme 2 (MFE-2), the peroxisomal bifunctional protein encoded by the HSD17B4 gene that catalyzes the hydration and dehydrogenation steps of peroxisomal fatty acid β-oxidation and also contributes to steroid metabolism. The unconjugated reagent is supplied at 100 µl and is validated for Western blot and immunohistochemistry workflows on human samples, supporting detection of MFE-2 in tissue lysates and fixed sections where the peroxisomal enzyme is being characterized. The polyclonal format allows recognition of multiple epitopes across the HSD17B4 polypeptide, an advantage when probing for expression differences linked to D-bifunctional protein deficiency, peroxisomal disorder studies, or fatty acid oxidation research. Researchers evaluating peroxisome biogenesis, β-oxidation pathway integrity, or steroid-processing capacity in human cells will find this reagent useful for both protein-level confirmation and tissue localization experiments.