Anti-Mevalonate Kinase Antibody

Raised in rabbit against the human mevalonate kinase enzyme, this polyclonal reagent from Antibodies.com supports research into cholesterol and isoprenoid biosynthesis pathways. Mevalonate kinase catalyzes an early ATP-dependent step in the mevalonate pathway, converting mevalonate to mevalonate-5-phosphate, and mutations in the encoding MVK gene are linked to mevalonate kinase deficiency and hyper-IgD syndrome. The unconjugated antibody is supplied as 100 µl of liquid in a vial and is validated for Western blot (WB) and immunohistochemistry (IHC) on human samples, giving laboratories flexibility to pair it with HRP, fluorophore, or biotin secondary reagents. Researchers studying sterol metabolism, peroxisomal disorders, or inflammatory signaling cascades can incorporate this reagent into standard immunoblotting and tissue-section workflows. Storage at standard short-term refrigerated conditions (4°C) preserves antibody activity for routine use, with aliquoting recommended to limit freeze-thaw cycles. Sufficient volume is provided for multiple blotting membranes or dozens of IHC slides depending on dilution.