Anti-METTL20 Antibody

METTL20 is a mitochondria-localized methyltransferase that catalyses lysine methylation of mitochondrial substrates and contributes to the post-translational regulation of oxidative phosphorylation machinery. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against the METTL20 target and is validated for Western blot and immunohistochemistry workflows on mouse and rat tissue. Researchers studying mitochondrial protein modification, metabolic regulation in skeletal muscle and brain, or the broader family of METTL-domain enzymes use the reagent to confirm expression patterns and to probe changes in METTL20 abundance under genetic or pharmacological perturbation. The antibody is supplied as a 100 µL liquid aliquot, sufficient for multiple blot and staining experiments when titred against endogenous antigen. Storage at 4 °C preserves activity for working use, and aliquoting on first thaw is recommended to limit freeze-thaw cycles. As a polyclonal reagent, the antibody recognises multiple epitopes on METTL20, which improves tolerance to minor antigen variation across the validated mouse and rat reactivity panel. The unconjugated format gives laboratories flexibility to couple the reagent to HRP, fluorophores, or biotin using standard secondary antibody protocols in both chromogenic and immunofluorescence detection contexts.