Anti-MET (phospho Y1234) Antibody

Phosphorylation of the MET receptor tyrosine kinase at tyrosine 1234 marks active receptor signaling, and this rabbit polyclonal antibody from Antibodies.com is raised specifically against that phospho-epitope for Western blot detection. The unconjugated IgG reagent recognizes human, mouse, and rat MET in cell lysates and tissue samples, enabling studies of HGF-driven MET pathway activation.

Y1234 sits within the kinase activation loop and serves as a key autophosphorylation site, so the antibody discriminates between quiescent and ligand-stimulated receptor pools. The 50 µl volume supports multiple blotting experiments, and polyclonal clonality broadens recognition around the modified residue.

Recommended handling includes aliquoting on receipt and storing refrigerated to preserve phospho-specific binding; avoid repeated freeze-thaw cycles. The antibody is unconjugated, leaving secondary antibody selection to the user, and the host species is rabbit for compatibility with common anti-rabbit secondaries.