Anti-MET (phospho Y1234) Antibody

The phospho-specific antibody from Antibodies.com targets MET receptor tyrosine kinase at tyrosine 1234, a key autophosphorylation site within the kinase activation loop that marks the receptor in its active signaling state. Raised in rabbit as a polyclonal IgG preparation, the reagent is supplied unconjugated in a 200 µl vial and is validated for Western blot (WB) and immunofluorescence (IF) workflows. Cross-reactivity is confirmed with human, mouse and rat samples, supporting studies of HGF/MET-driven pathways in cell proliferation, migration, epithelial-mesenchymal transition, and tumor invasion across multiple model systems. The unconjugated format allows flexible pairing with secondary reagents of the researcher's choice, including HRP-labeled or fluorophore-conjugated detectors for chemiluminescent or imaging-based readouts. For storage, the antibody should be kept frozen at -20 °C in small aliquots to protect the phospho-epitope from dephosphorylation and to limit loss of activity across repeated freeze-thaw cycles. This reagent is intended for research use only and is suited to investigations of MET activation in cancer biology, receptor signaling, and kinase pharmacology.