Anti-MET (phospho Y1003) Antibody

This rabbit polyclonal antibody from Antibodies.com selectively recognizes the phosphorylated form of the MET receptor tyrosine kinase at tyrosine residue 1003 (pY1003), a site in the juxtamembrane region whose phosphorylation recruits the Cbl ubiquitin ligase and drives receptor internalization. Raised in rabbit and purified as an IgG immunoglobulin, the reagent is supplied unconjugated in a 100 µl vial, ready for direct incorporation into Western blot and immunofluorescence workflows on human, mouse, and rat samples. Researchers studying HGF/MET signalling, receptor downregulation, and downstream PI3K-Akt or Ras-MAPK pathway activity can use this antibody to monitor activation-state changes following ligand stimulation or inhibitor treatment.