Anti-MEST Antibody

The Anti-MEST Antibody from Antibodies.com is a rabbit polyclonal reagent raised against the mesoderm-specific transcript protein, a paternally expressed imprinted gene product also known as PEG1. Supplied as 100 µl of an unconjugated preparation at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, this Primary Antibody is validated for Western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples.

MEST is a key regulator of fat mass expansion and adipocyte differentiation, and altered expression or loss of imprinting at the MEST/PEG1 locus has been documented in several human cancers, making reliable detection in fixed and frozen tissue sections a recurring need in obesity, developmental, and oncology research. Researchers commonly apply this antibody to western blot lysates to confirm the expected band near 38 kDa, and to formalin-fixed paraffin-embedded sections for IHC localization studies. The polyclonal format is well suited to IF staining where signal amplification improves sensitivity for low-abundance targets.

Storage recommendations are to keep the vial refrigerated at 4 °C for short-term use and to aliquot the glycerol-containing stock for longer-term storage at -20 °C, avoiding repeated freeze-thaw cycles that can degrade polyclonal activity. Each vial is intended for research use only and ships as a single-use format from Antibodies.com.