Anti-MEP1B Antibody

This polyclonal antibody from Antibodies.com is raised in rabbit and specifically targets MEP1B (meprin β subunit), a zinc-dependent endopeptidase of the astacin metalloprotease family expressed predominantly in intestinal and renal epithelial tissue. The reagent is supplied as an unconjugated IgG in a 200 µl volume, validated for Western blot detection of mouse MEP1B in tissue lysates and cell extracts. Meprin β participates in extracellular matrix remodeling, cytokine shedding at the cell surface, and inflammatory signaling cascades; researchers use this reagent to study epithelial barrier function, dextran sulfate sodium-induced colitis models, and acute kidney injury pathways. The polyclonal format allows recognition of multiple epitopes on MEP1B, supporting robust signal across a range of sample preparation conditions. For storage, the antibody should be kept refrigerated with aliquots prepared on first use to limit freeze-thaw cycles and preserve activity across long-term studies.