Anti-MEP1B Antibody

This polyclonal primary antibody from Antibodies.com targets MEP1B (Meprin A subunit beta), a zinc-dependent metalloendopeptidase expressed in epithelial tissues including kidney brush border membranes and intestinal epithelium. The antibody is raised in rabbit and is provided as an unconjugated IgG preparation in a vial of 100 µl, suitable for western blot detection of mouse MEP1B protein in research samples.

MEP1B contributes to extracellular matrix remodeling through cleavage of substrates such as collagen IV, fibronectin, and certain growth factors, and the enzyme has been studied in contexts ranging from inflammatory bowel disease models to renal fibrosis. Because the reagent is reactive specifically with mouse MEP1B, it is useful for experiments in murine cell lines, primary tissue lysates, and gene-knockout comparison studies where meprin expression is being characterized. The unconjugated format allows researchers to pair it with their own choice of secondary antibodies for chemiluminescent or fluorescent western blot workflows.