Anti-MEOX1 Antibody

Hailing from the developmental biology and skeletal muscle research reagent family, this unconjugated rabbit polyclonal IgG preparation from Antibodies.com targets the MEOX1 (Mesenchyme Homeobox 1) homeodomain transcription factor, which plays an essential role in somite segmentation, vertebral column patterning, sclerotome differentiation, and early myogenic lineage specification during embryogenesis. The reagent is supplied as a 100 µl vial of affinity-purified antibody formulated in PBS containing 0.02% sodium azide, generated against a 19 amino acid synthetic peptide mapped near the central region of human MEOX1 (UniProt P50221). Validated for Western blot and immunofluorescence workflows across human, mouse, and rat samples, the polyclonal pool recognizes multiple epitopes on the ~28 kDa target protein, supporting robust signal detection in whole-cell lysates, transfected 293T lysates, and tissue cryosections including skeletal muscle and liver. Storage at -20 °C is recommended, with avoidance of repeated freeze-thaw cycles to preserve antibody activity, and unconjugated format offers flexibility for downstream labeling with fluorophores, HRP, or biotin depending on experimental design. Researchers investigating Klippel-Feil syndrome-associated variants, paraxial mesoderm specification, and myogenic regulatory networks rely on this primary antibody from Antibodies.com to localize MEOX1 in developmental models and confirm expression changes in cell-based differentiation assays.