Anti-MEK1 (phospho-T286) Antibody

This rabbit polyclonal antibody from Antibodies.com targets a phosphorylated threonine (T286) epitope of MEK1, the MAP kinase/ERK kinase 1 (MAP2K1) that operates within the canonical Ras-RAF-MEK-ERK signaling cascade. The reagent selectively recognizes MEK1 only when threonine 286 is phosphorylated, allowing researchers to monitor activation-state dynamics rather than total protein abundance. It is validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples, supporting cross-species investigations in signal transduction, cancer biology, and neuroscience. The product is supplied as 100 µl of liquid at 1 mg/ml in PBS with 0.1% sodium azide as a preservative and 50% glycerol as a cryoprotectant, and is unconjugated so that secondary detection chemistries (HRP, fluorophore, or biotin) can be chosen to match the assay.