Anti-MEK1 / MEK2 (Ab-217 / 221) Antibody

Offered through Antibodies.com, this affinity-purified reagent is a rabbit polyclonal preparation raised against a synthetic peptide spanning residues215–219/219–223 (I-D-S-M-A) of human MEK1/MEK2, and it specifically recognizes the endogenous levels of total MEK1 and MEK2 protein. Supplied as an unconjugated antibody at 1.0 mg/mL in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol, the 50 µl pack size is intended for use in Western blot (WB), immunohistochemistry (IHC) and immunocytochemistry/immunofluorescence (ICC/IF) workflows. The antibody has been validated on human, mouse and rat samples, making it a versatile option for signal-transduction studies of the MAPK cascade. For best results, the vial is shipped at 4 °C and should be aliquoted upon arrival and stored long-term at -20 °C, with repeated freeze/thaw cycles avoided to preserve activity. As a research-use-only reagent from the Antibodies.com catalogue, it provides a reliable tool for probing dual-specificity MAP kinase kinase 1/2 (also referred to as MAP2K1, MAPKK1, MKK1 or ERK activator kinase) in cell and tissue preparations.