Anti-MEK1 (Ab-291) Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent, this unconjugated primary antibody recognizes MAP2K1 (MEK1), the dual-specificity kinase that sits directly upstream of ERK1/2 in the canonical Ras-Raf-MEK-ERK signaling cascade. The epitope corresponds to a region around residue 291 of the human MEK1 protein.

Validated for Western blot (WB) and immunohistochemistry (IHC), the reagent shows reactivity against human, mouse, and rat samples, supporting cross-species studies of MAPK pathway activity in cultured cell lysates and fixed tissue sections. It is supplied as 100 µl of unconjugated antiserum, suitable for pairing with HRP-, fluorophore-, or biotin-conjugated secondary antibodies selected by the end user.

Store aliquots refrigerated and avoid repeated freeze-thaw cycles to preserve binding activity; for short-term bench use, keep on ice. Intended for research use only.