Anti-MEFV Antibody

Pyrin, the protein product of the human MEFV gene located on chromosome 16p13.3, is the target of this rabbit polyclonal IgG primary antibody from Antibodies.com. The reagent is supplied as 200 µl of unconjugated stock and is validated for Western blot analysis of human MEFV expression. MEFV mutations underlie familial Mediterranean fever and related autoinflammatory conditions through dysregulation of the NLRP3 inflammasome, so this antibody supports research into FMF pathogenesis, carrier biology, and downstream cytokine signaling. The polyclonal format recognizes multiple epitopes across the pyrin sequence, and the rabbit host species is compatible with standard immunoblotting membranes and chemiluminescent detection systems. For best results, store aliquots at -20°C in single-use fractions to limit freeze-thaw cycles; the reagent is intended for research use only.