Anti-MEF2A (phospho T312) Antibody

Produced in rabbit as a polyclonal IgG reagent, this phospho-specific antibody from Antibodies.com detects MEF2A when the transcription factor is phosphorylated at threonine 312, a regulatory site within its transactivation domain. Phosphorylation at this residue, driven by p38 MAPK signaling, increases MEF2A-driven transcription and connects the protein to calcium/calmodulin-dependent kinase cascades, stress-responsive gene programs, and differentiation across cardiac, skeletal muscle, and neuronal cell types.

Validated for immunohistochemistry (IHC) and immunofluorescence (IF) workflows, the reagent cross-reacts with human, mouse, and rat samples, supporting comparative studies across standard model organisms. The polyclonal backbone is designed to recognize the pT312 phospho-epitope, and the unconjugated format lets researchers pair it with their preferred secondary detection chemistry.

Supplied as 50 µl of unconjugated antisera (single use), the antibody is intended for research use only. For best stability, aliquot upon arrival and store frozen at -20 °C; protect from light and minimize freeze-thaw cycles to preserve phospho-specific binding activity over the shelf life of the reagent.