Anti-MEF2a (Ab-312) Antibody

This polyclonal antibody from Antibodies.com targets MEF2a, a MADS-box transcription factor that governs muscle differentiation, cardiac morphogenesis, and neuronal gene expression. The reagent is raised in rabbit and recognizes an epitope surrounding residue 312 of the human MEF2a protein, supporting studies of site-specific post-translational modification in cell signaling pathways.

Supplied as 100 µl of unconjugated antiserum, the antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows. Cross-species reactivity has been confirmed against human, mouse, and rat samples, enabling comparative work in cardiovascular, skeletal muscle, and neuroscience laboratories. For Western blot, the reagent can detect endogenous MEF2a in cell lysates and tissue homogenates; for IHC, it supports localization studies on paraformaldehyde-fixed tissue sections.

For handling, store the vial frozen at -20 °C in small aliquots to minimize freeze-thaw cycles and preserve antibody activity over time. The polyclonal nature of this reagent provides broader epitope coverage than monoclonal alternatives, which can be advantageous when detecting low-abundance transcription factors in research use only settings.