Anti-MEF-2C Antibody

The polyclonal antibody from Antibodies.com targets MEF-2C, a MADS-box transcription factor encoded by the MEF2C gene and central to cardiac morphogenesis, skeletal muscle differentiation, and neuronal development. Raised in rabbit, this unconjugated reagent is validated for Western blot, immunohistochemistry, and ELISA workflows, and it cross-reacts with human and mouse samples. Each vial supplies 100 µL of polyclonal antiserum, providing a working volume sufficient for probing tissue lysates or fixed sections across multiple experimental runs. MEF-2C is studied extensively in cardiovascular biology, myogenesis, and neurodevelopmental disorder research, including investigations into autism spectrum disorder and intellectual disability linked to MEF2C haploinsufficiency. The polyclonal format broadens epitope recognition across the protein, supporting detection of full-length MEF-2C and downstream isoform analyses in cell-line and primary-tissue models. Researchers commonly deploy this reagent to characterize MEF2C expression during cardiomyocyte maturation, to map neuronal populations in cortical development, and to probe transcriptional programs in activated lymphocytes. For best results, store the vial refrigerated between uses and minimize freeze-thaw cycles to preserve antibody activity.