Anti-MED23 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets Mediator Complex Subunit 23 (MED23), a core component of the multiprotein Mediator complex that bridges DNA-bound transcription factors with RNA polymerase II during regulated transcription. Supplied as 50 µl of unconjugated IgG, the reagent is validated for Western blot detection of MED23 in human, mouse, and rat samples, supporting studies of transcriptional coactivation, chromatin signaling, and the developmental roles of the Mediator complex.

MED23, also referenced in published work as CRSP3 and DRIP130, contributes to ligand-activated transcription through nuclear receptors and several kinase-driven signaling cascades. Studies probing Mediator-dependent gene regulation, embryonic phenotypes linked to subunit loss, or pathway-focused expression analysis can apply the polyclonal reagent to whole-cell lysates from cultured mammalian cells and primary tissue. The unconjugated format integrates with standard Western blot workflows using HRP- or fluorophore-conjugated secondary antibodies, while the rabbit host helps minimize cross-reactivity in commonly used experimental model systems.