Anti-MED22 Antibody

The MED22 subunit sits within the head module of the Mediator complex, a multi-protein assembly that transmits regulatory signals from DNA-bound transcription factors to RNA polymerase II. This unconjugated rabbit polyclonal reagent from Antibodies.com detects the endogenous MED22 protein in human and mouse samples by western blot and immunohistochemistry on fixed tissue sections. Supplied as 100 µl of ready-to-use reagent, the antibody supports studies of transcriptional regulation, chromatin dynamics, and the integration of signalling pathways at gene promoters. Because MED22 is conserved between human and mouse, the reagent also enables comparative work in cell culture models and tissue samples derived from both species, while the unconjugated format lets researchers conjugate it to fluorophores or enzymes of their own choosing for custom detection workflows. The polyclonal mixture offers recognition of multiple epitopes, which can help when probing low-abundance transcription complexes or nuclear extracts. This product is intended for research use only and is not validated for diagnostic or therapeutic applications.