Anti-MED18 Antibody

The MED18 protein is a subunit of the Mediator complex, a large multi-protein assembly that bridges transcription factors with RNA polymerase II to regulate gene expression. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against human MED18 and is validated for Western blot and immunohistochemistry workflows, enabling detection of endogenous MED18 in human tissue sections and cell lysates.

Supplied as 100 µl of polyclonal antiserum, the reagent can be paired with HRP- or fluorophore-conjugated secondary antibodies for chemiluminescent or immunofluorescence detection. MED18 (also designated p28b in some literature) associates with the Mediator head module alongside subunits such as MED20 and MED22, and functional studies have linked its activity to transcriptional activation of specific gene sets in human cells.