Anti-MED15 Antibody

A subunit of the mammalian Mediator complex, MED15 functions as a transcriptional coactivator that bridges regulatory transcription factors with RNA polymerase II. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against MED15 and is validated for Western blot detection in human, mouse, and rat samples.

Supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, the antibody is packaged as a 100 µl vial. MED15 is also referenced in the literature as ARC105 or PCQAP and has been studied in the context of adipogenesis, lipid metabolism, and T-cell receptor signaling, where it interfaces with factors including SREBP and SMAD proteins.

For routine handling, refrigerate the vial and protect from light; aliquoting before storage limits freeze-thaw cycles and helps preserve antibody binding activity over time. Researchers investigating transcriptional regulation, mediator complex assembly, or pathway crosstalk can apply this reagent to probe MED15 protein levels in whole-cell extracts and tissue lysates.