Anti-MECOM Antibody

This polyclonal antibody from Antibodies.com targets MECOM (MDS1 and EVI1 complex locus), a zinc finger transcription factor encoded on chromosome 3q26 that governs hematopoietic stem cell self-renewal and myeloid differentiation. Raised in rabbit and supplied as an unconjugated reagent in a 100 µL vial, it is validated for Western blot and immunohistochemistry workflows on human samples. MECOM dysregulation is recurrently observed in acute myeloid leukemia, myelodysplastic syndromes, and 3q26 chromosomal rearrangements, so reliable detection supports leukemia research, biomarker characterization, and studies of hematopoietic lineage commitment. Because the reagent is polyclonal, it recognizes multiple epitopes across the target protein, helping deliver consistent staining in fixed tissue sections and clear bands during immunoblotting. Researchers should store the antibody refrigerated, protect it from light, and avoid repeated freeze-thaw cycles to preserve reactivity across experiments.