Anti-ME1 Antibody

Raised in rabbit against cytosolic Malic Enzyme 1, this unconjugated polyclonal primary antibody detects the NADP-dependent metabolic enzyme ME1 in human samples. ME1 catalyzes the oxidative decarboxylation of malate to pyruvate while supplying NADPH for lipid biosynthesis and cellular redox homeostasis, making it a frequent target in studies of cancer metabolism, adipogenesis, and oxidative stress signaling.

Distributed by Antibodies.com as 100 µl of liquid, the reagent is validated for Western blot and immunofluorescence workflows. Researchers apply it to probe endogenous ME1 expression across cell lines and tissue sections, including fixed-cell imaging experiments where the unconjugated format pairs with chosen fluorescent secondary antibodies. The polyclonal nature of the reagent broadens epitope coverage, supporting detection in lysates that may vary in post-translational modification state.

For best results, store refrigerated, protect from light, and limit freeze-thaw cycles by aliquoting upon first use. The antibody is intended for research use only and is reactive with human ME1.