Anti-MDM4 Antibody

Produced in rabbit and supplied by Antibodies.com, this polyclonal primary antibody targets MDM4 (alternatively named MDMX or HDMX), an essential negative regulator within the p53 tumor suppressor pathway that is central to cancer biology and DNA damage response research. The reagent is provided as 200 µl of unconjugated IgG in a format appropriate for routine immunoblotting workflows, with demonstrated reactivity toward human MDM4 in Western blot applications. Because the antibody is polyclonal, it recognizes several epitopes on the target, which can assist in detecting both full-length MDM4 and reported splice variants of interest to researchers studying the MDM2–MDM4–p53 signaling axis. The unconjugated formulation offers flexibility in selecting detection reagents and optimizing signal-to-background in standard laboratory protocols focused on oncogene amplification events, p53 reactivation strategies, or tumor cell signaling studies.