Anti-MCP3 Antibody [490]

Mouse monoclonal clone 490 from Antibodies.com targets Monocyte Chemotactic Protein 3 (MCP-3, also designated CCL7), a CC-family chemokine secreted by macrophages, fibroblasts, and endothelial cells that drives monocyte and dendritic cell recruitment to sites of inflammation. This unconjugated primary reagent is validated for Western Blot on human samples and supplied as a lyophilised 100 µg vial that reconstitutes cleanly for downstream chemokine detection workflows.

MCP-3 functions in monocyte-attracting signaling and is studied in inflammatory disease models, tumor microenvironments, and leukocyte trafficking, where it acts alongside related ligands such as CCL2 and CCL5 through shared G-protein coupled receptors. Researchers can probe endogenous MCP-3 expression in cell lysates, characterize chemokine signaling cascades, and investigate the molecule's contribution to innate immune responses. The unconjugated IgG1 format offers flexibility for custom HRP, biotin, or fluorophore labeling depending on the chosen secondary detection strategy.

Supplied lyophilised from Antibodies.com, the antibody should be reconstituted in sterile buffer per protocol, stored refrigerated, and handled with standard cold-chain care to preserve activity across multiple freeze-thaw cycles. Intended for research use only.