Anti-MCM6 Antibody

Antibodies.com offers a rabbit polyclonal antibody raised against MCM6 (Minichromosome Maintenance Complex Component 6), a core subunit of the MCM2-7 replicative helicase that unwinds parental DNA at licensed replication origins during S phase. The unconjugated reagent is supplied as 100 µl of liquid and has been validated for western blot, immunohistochemistry, and immunofluorescence work on human, mouse, and rat specimens.

Because MCM6 transcription rises in actively cycling cells and falls upon quiescence or differentiation, the antibody is frequently deployed as a proliferation marker in tumor pathology, DNA replication licensing studies, and cell cycle re-entry assays. The polyclonal format provides epitope redundancy helpful when probing denatured lysates, formalin-fixed paraffin-embedded sections, or methanol-fixed cells. Delivered unconjugated, the reagent can be paired with HRP-conjugated, fluorophore-labeled, or biotinylated secondary antibodies to fit existing imaging and blotting pipelines.