Anti-MCM4 Antibody

The MCM2-7 replicative helicase complex that licenses origins of DNA replication in eukaryotic cells depends on its MCM4 subunit for proper assembly and function. This rabbit polyclonal antibody, supplied by Antibodies.com in a 100 µl vial, is raised against MCM4 and validated for western blot and immunohistochemistry on human, mouse, and rat samples. As an unconjugated primary reagent, it enables flexible assay design with user-chosen reporter chemistries, and it detects the target under denaturing conditions in WB while supporting chromogenic localization of the protein in fixed tissue sections by IHC. Researchers have used anti-MCM4 antibodies to investigate cell cycle entry, replication licensing, chromatin-bound replication complexes, and altered MCM4 expression as a candidate biomarker in proliferative disorders and a range of tumor types. Aliquot upon receipt, refrigerate, and protect from repeated freeze-thaw cycles to preserve immunoreactivity. Intended for research use only.