Anti-MCM3 Antibody

Raised in rabbit against MCM3, this polyclonal antibody targets minichromosome maintenance complex component 3, a core subunit of the MCM2-7 replicative helicase that licenses replication origins and supports S-phase entry. Antibodies.com supplies the reagent at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl aliquot that can be added directly to standard immunoassay workflows. Validated applications include western blot analysis, immunohistochemistry on fixed tissue sections, and immunofluorescence on cultured cells, with demonstrated reactivity against human, mouse, and rat samples. Because MCM3 expression rises in actively dividing cells, the antibody is frequently used as a proliferation marker in tumor biology, stem cell, and cell cycle studies, often alongside Ki-67 readouts. The unconjugated format leaves secondary reagent choice open, allowing pairing with HRP, fluorescent, or biotinylated detection systems depending on the assay design.