Anti-Mcl-1 (S155) Antibody

The Antibodies.com anti-Mcl-1 (S155) polyclonal reagent is a rabbit host primary antibody raised against the S155 epitope region of myeloid cell leukemia-1 (Mcl-1), an anti-apoptotic Bcl-2 family member that regulates mitochondrial outer membrane permeabilization. Supplied as 50 µl of an unconjugated, affinity-purified preparation at 1 mg/ml in phosphate buffered saline (pH 7.2) with 0.05% sodium azide as preservative, the reagent is validated for immunohistochemistry (IHC) on formalin-fixed tissue sections and shows cross-reactivity with both human and mouse samples. Each vial is intended for research use only and should be kept refrigerated; aliquoting on first use helps limit freeze-thaw cycles that can degrade polyclonal sera. Researchers studying apoptosis, chemoresistance, lymphoma biology, and BCL-2 pathway signaling commonly deploy this antibody to assess Mcl-1 expression patterns in tumor biopsies and matched normal tissue controls.