Anti-MCC Antibody

Raised in rabbit and supplied by Antibodies.com as an unconjugated polyclonal IgG reagent, this antibody targets the Mutated in Colorectal Cancer (MCC) protein, a tumor suppressor best known for its role in colorectal tumorigenesis where it modulates the Wnt/β-catenin signaling cascade. The 100 µl format is intended for immunohistochemistry on human tissue, supporting studies that localize MCC expression in normal mucosa, adenomatous lesions, and carcinomas to investigate loss of this regulator during tumor progression. Because the reagent is polyclonal, it recognizes multiple epitopes across the MCC protein, which can be useful when comparing expression patterns across variable tissue samples. Researchers applying it to formalin-fixed, paraffin-embedded sections can use standard chromogenic or fluorescent detection workflows, since the antibody is supplied unconjugated and accepts a wide choice of secondary labels. The product is intended for research use only, complementing molecular assays aimed at defining how MCC contributes to epithelial cell homeostasis and oncogenic transformation beyond the colorectal setting.