Anti-MCAM Antibody

This rabbit polyclonal antibody from Antibodies.com targets MCAM (Melanoma Cell Adhesion Molecule), a ~113 kDa transmembrane glycoprotein of the immunoglobulin superfamily also designated CD146. Validated for Western blot and immunohistochemistry on human tissue, the unconjugated IgG reagent is supplied as 100 µl and supports studies of angiogenesis, pericyte biology, tumor invasion, and vascular remodeling.

MCAM/CD146 is widely used as a marker for endothelial cells, mesenchymal stem cells, and pericytes, making this reagent useful for characterizing CD146-positive populations in developmental, regenerative, and oncology research. The polyclonal format offers broad epitope recognition across both the extracellular and intracellular regions of MCAM, which is helpful when probing protein expression in fixed tissue sections via immunohistochemistry or in cell lysates via Western blot. For research use only; refrigerate upon receipt and aliquot to limit repeated freeze-thaw cycles of the antibody stock.