Anti-MC4R Antibody

Melanocortin 4 Receptor (MC4R) is a G protein-coupled receptor expressed primarily in hypothalamic neurons, where it plays a central role in regulating energy homeostasis, satiety signaling, and body weight. Mutations in MC4R are the most common monogenic cause of severe early-onset obesity, making the receptor a focal target in metabolic and neuroscience research.

This unconjugated rabbit polyclonal IgG antibody from Antibodies.com is raised against MC4R and validated for western blot detection of the receptor in human, mouse, and rat samples. Provided as a 50 µL liquid aliquot in a single vial, the reagent supports studies of melanocortin pathway signaling, appetite regulation, and obesity-related mechanisms.

For best results, store the antibody frozen at -20 °C, protect from light, and limit freeze-thaw events to preserve binding activity across multiple experiments.