Anti-MC1R Antibody

This rabbit polyclonal reagent targets the melanocortin-1 receptor (MC1R), a G protein-coupled receptor that regulates pigmentation through α-melanocyte-stimulating hormone signaling. Raised in rabbit and supplied as an unconjugated antiserum in a 100 µl vial, the antibody supports Western blot and immunohistochemistry workflows on human and mouse samples. MC1R is widely studied in melanocyte biology, cutaneous photobiology, and melanoma research, where loss-of-function variants are linked to red hair, fair skin, freckling, and elevated UV-induced carcinogenesis risk. The reagent is offered by Antibodies.com as part of their Primary Antibodies portfolio and is suitable for both Western blot band detection of the approximately 37 kDa receptor and IHC localization in skin, melanoma, and related tissue sections. Researchers investigating pigmentation genetics, melanocortin signaling pathways, or GPCR expression in cutaneous and immune cell populations can use this polyclonal antibody to probe endogenous receptor levels across species-relevant model systems.