Anti-MAVS Antibody

This polyclonal reagent from Antibodies.com is raised in rabbit against MAVS (Mitochondrial Anti-Viral Signaling protein), a 540-amino-acid adaptor anchored on the outer mitochondrial membrane that drives type I interferon signaling through the RIG-I / MDA5 pathway. Supplied as an unconjugated antiserum in a 100 µl vial, the antibody is validated for Western blot and immunohistochemistry workflows on human samples, where it is used to detect endogenous MAVS in cell lysates, paraffin-embedded tissue sections, and enriched mitochondrial fractions. Because MAVS sits at the interface of innate immunity and mitochondrial biology, researchers in antiviral signaling, inflammasome activation, apoptosis, and RIG-I-like receptor (RLR) research apply this reagent to probe expression, oligomerization, prion-like aggregation, and proteolytic cleavage of MAVS following viral infection, RNA transfection, or apoptotic challenge.