Anti-MATR3 Antibody

Matrin 3 (MATR3) is an RNA- and DNA-binding protein that organizes the nuclear matrix and supports pre-mRNA processing and spliceosome assembly. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against MATR3 and validated for western blot (WB) and immunohistochemistry (IHC) workflows, with reactivity demonstrated against human, mouse, and rat samples.

The antibody is supplied as 100 µl of a 1 mg/ml stock formulated in PBS with 0.1% sodium azide and 50% glycerol, ready to dilute into standard immunodetection buffers. Researchers studying ALS-linked RNA-binding proteins, nuclear matrix architecture, or MATR3-associated distal myopathy pathways can apply it to lysate blots or to fixed tissue sections to localize endogenous nuclear MATR3.

As a polyclonal reagent, it recognizes multiple MATR3 epitopes, which improves tolerance to minor denaturation differences between sample preparations and helps when probing endogenous MATR3 versus truncated disease-associated isoforms. Aliquot upon first use and store frozen; avoid repeated freeze-thaw cycles to preserve binding activity. Protect from light and handle with standard sodium azide precautions.