Anti-MATK Antibody

The MATK (Megakaryocyte-Associated Tyrosine Kinase) polyclonal antibody from Antibodies.com is raised in rabbit and supplied as an unconjugated IgG preparation at 100 µl per vial. It recognizes MATK across human, mouse, and rat samples, supporting comparative studies of megakaryocyte lineage cells, platelet biogenesis, and Src-family kinase signaling in hematopoietic systems. MATK, also known as CTK or HYL, is a non-receptor tyrosine kinase implicated in negative regulation of megakaryocyte differentiation and signaling downstream of the c-Kit receptor.

Validated for Western blot and immunohistochemistry workflows, this Primary Antibody supports investigation of MATK expression in bone marrow, lymphoid tissue, and leukemia-derived cell lines. Researchers studying megakaryocytopoiesis, platelet formation, and downstream signaling cascades can use it to characterize MATK phosphorylation status, its relationship with STAT3 substrates, and subcellular distribution in normal and transformed hematopoietic cells. Polyclonal reactivity provides broad epitope coverage when probing conserved kinase domains across the three reactive species, and the unconjugated format allows flexible labeling with secondary reagents of choice.

Store the vial refrigerated in working aliquots to minimize freeze-thaw cycles and preserve IgG activity. Brief centrifugation before opening recovers the full 100 µl volume for downstream blotting and staining applications.