Anti-MAPKAPK5 Antibody

This polyclonal reagent from Antibodies.com targets MAPKAPK5, a serine/threonine kinase also known as PRAK that operates downstream of p38 MAPK and JNK signaling cascades. Raised in rabbits and supplied as an IgG preparation at 200 µl, the antibody is unconjugated and validated for western blot detection of the human protein. MAPKAPK5 participates in cellular stress responses, cytoskeletal remodeling, and autophagy regulation, supporting research into kinase pathway crosstalk, inflammation-related signaling, and tumor-suppressor biology. The polyclonal format allows recognition of multiple epitopes on MAPKAPK5, an advantage when working with denatured lysate samples or probing post-translational modifications such as activating phosphorylation by upstream MAPKs. Investigators studying p38-driven transcription, oxidative stress adaptation, or cytoskeletal dynamics commonly rely on unconjugated primary antibodies of this type. The unconjugated IgG offers flexibility for downstream detection strategies in the western blot workflow, including pairing with HRP-, fluorophore-, or biotin-conjugated secondary reagents chosen by the laboratory. Product format is a single 200 µl vial prepared from rabbit serum for use in western blot applications against human MAPKAPK5.