Anti-MAPKAP1 Antibody

Raised in rabbit against the MAPKAP1 target, this polyclonal IgG reagent from Antibodies.com is supplied as an unconjugated 200 µl aliquot for western blot detection of the human protein. MAPKAP1, also known as SIN1, is a core component of the mTORC2 complex and a downstream effector of PI3K signaling, where it contributes to AKT phosphorylation at serine 473 and links growth-factor cues to cytoskeletal remodeling, cell survival and metabolic control.

The antibody is validated for use on human samples and is compatible with standard PVDF or nitrocellulose membranes following SDS-PAGE separation of whole-cell lysates. Researchers studying mTOR pathway activity, insulin signaling, or downstream readouts of cellular stress frequently pair this reagent with phospho-specific AKT antibodies to monitor mTORC2-dependent phosphorylation events. For long-term integrity, keep the vial refrigerated, protect it from light, aliquot on first use, and limit freeze-thaw cycles to preserve titer across multiple western blot experiments. Intended for research use only.