Anti-MAPK7 Antibody

MAPK7, also designated ERK5, is a member of the mitogen-activated protein kinase family that participates in signaling cascades governing cell proliferation, differentiation, and stress responses. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human MAPK7 target and is validated for Western blot and immunohistochemistry workflows, supporting studies of MAPK signaling in cell biology and oncology research.

The antibody is supplied as 100 µL of liquid stock, sufficient for multiple blotting or staining experiments. As a polyclonal reagent, it binds several epitopes across the MAPK7 protein, which can be advantageous when detecting low-abundance targets or working with samples that may carry post-translational modifications such as phosphorylation. Researchers investigating upstream regulators, downstream transcription factor activity, or cross-talk between MAPK pathways can apply this reagent to probe ERK5 activation status in cultured human cells and tissue sections.

Typical uses include Western blot analysis of whole-cell lysates to confirm ERK5 expression and phosphorylation state, alongside immunohistochemistry on formalin-fixed paraffin-embedded tissue to localize MAPK7 in tumor or normal specimens. Storage at 4 °C is appropriate for short-term use; for longer term storage, follow standard antibody handling and avoid repeated freeze-thaw cycles to preserve reagent performance.