Anti-MAPK14 (phospho T180) Antibody

This polyclonal antibody from Antibodies.com is raised in rabbit and selectively recognizes MAPK14 (also known as p38 alpha MAPK) only when phosphorylated at threonine 180, a residue in the kinase activation loop that becomes dually phosphorylated together with Y182 during stress signaling. The reagent is supplied as 50 µl of unconjugated IgG in a single-use vial, intended for research use only and validated for Western blot and immunofluorescence workflows on human and rat samples.

Dual T180/Y182 phosphorylation drives p38 alpha activation downstream of inflammatory cytokines, osmotic shock, and UV exposure, making this phospho-specific reagent useful for tracking pathway engagement in studies of inflammation, apoptosis, and the cellular stress response. Shipped refrigerated, with long-term storage at -20 °C in single-use aliquots to limit freeze-thaw cycles and preserve phospho-epitope reactivity, the antibody provides a sensitive read-out of acute MAPK14 activation in cell-based and tissue-based assays.