Anti-MAPK14 (phospho T180) Antibody

This rabbit polyclonal reagent from Antibodies.com detects MAPK14 (p38α MAPK) only when threonine 180 is phosphorylated, the key activation-loop residue whose phosphorylation (along with Y182) drives full kinase activity during cellular stress responses. Supplied as a 200 µl vial of unconjugated IgG validated for western blot and immunofluorescence, the antibody has been characterized against human and rat samples. Polyclonal coverage of the phospho-T180 epitope provides robust recognition of the activated kinase in signaling studies, inflammation research, and investigations of p38 pathway involvement triggered by cytokines, UV exposure, or osmotic shock. Researchers apply it to probe cell lysates, fixed tissue sections, and other experimental systems in studies of stress-activated MAP kinase cascades, where confident identification of the phosphorylated form supports mechanistic interpretation.