Anti-MAPK12 Antibody

This unconjugated rabbit polyclonal IgG antibody targets MAPK12, a serine/threonine kinase of the p38 MAP kinase family also known as p38γ or ERK6. The kinase is expressed across many tissues with higher levels in skeletal muscle and contributes to stress-activated signaling, myoblast differentiation, and inflammatory responses.

Supplied as a 200 µl liquid aliquot, the reagent is validated for western blot (WB) and immunohistochemistry (IHC) on human and mouse samples. Researchers use it to probe MAPK12 phosphorylation status, downstream ATF2 and c-Jun activation, and the kinase's role in cardiac hypertrophy models, metabolic regulation, and tumor microenvironment studies.

Manufactured by Antibodies.com, this primary antibody is raised in rabbit and affinity-purified to IgG. The unconjugated format allows flexible pairing with HRP-, biotin-, or fluorophore-labeled secondary reagents. For storage, aliquot upon arrival and store at -20 °C to avoid repeated freeze-thaw cycles; keep working aliquots at 4 °C during active use and protect from light when the application calls for fluorescent detection.