Anti-MAPK12 Antibody

Antibodies.com offers this rabbit polyclonal antibody raised against MAPK12 (Mitogen-Activated Protein Kinase 12), also referred to as p38γ or ERK6, a serine/threonine kinase in the MAP kinase family that participates in cellular stress responses, myoblast differentiation, and inflammatory signaling cascades.

The unconjugated IgG reagent is supplied in a 100 µL vial and is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human and mouse samples. Because MAPK12 expression is frequently examined in the context of skeletal muscle biology, cardiac stress models, and several cancer cell lines, researchers commonly pair this reagent with lysates from differentiated myotubes, tumor-derived cell lines, or tissue sections where MAP kinase pathway activity is of interest.

For best results, aliquot upon first use to limit freeze-thaw cycles and store the vial refrigerated at 4°C for short-term handling; long-term storage at -20°C is appropriate for the antibody stock. The polyclonal format allows recognition of multiple epitopes across the MAPK12 protein, which can be useful when probing for the full-length kinase as well as processed or alternatively spliced variants. Lot-specific validation data and recommended working dilutions are provided on the accompanying datasheet from Antibodies.com.