Anti-MAPK10 Antibody

Raised in rabbit against the MAPK10 kinase domain, this unconjugated polyclonal reagent targets the neuron-enriched JNK3 isoform and supports studies of stress-activated signaling in human samples. Antibodies.com supplies the antibody as a 100 µl liquid aliquot suited to multiple immunodetection workflows including Western blot, immunohistochemistry, and immunofluorescence.

MAPK10 (also called JNK3) participates in the c-Jun N-terminal kinase cascade and is linked to neuronal apoptosis, excitotoxic injury, and models of neurodegeneration, making it a relevant marker for neuroscience and cancer research programs. Because the reagent is affinity-purified, it can be paired with secondary reporters of the user's choice and applied to fixed or frozen tissue sections, cultured cell lines, and lysate-based protein blots.

Handling recommendations include brief refrigerated storage and protection from light to preserve activity through repeated freeze-thaw cycles. Researchers evaluating MAPK10 phosphorylation dynamics or isoform-specific expression will find the polyclonal formulation useful for capturing multiple epitopes of the target across reactive human tissues.